Publications

Bleedings and thrombosis

Genome-wide association study of direct oral anticoagulants and their relation to bleeding

https://pubmed.ncbi.nlm.nih.gov/40116934/

Genetic determinants of apixaban plasma levels and their relationship to bleeding and thromboembolic events

https://pubmed.ncbi.nlm.nih.gov/36186466/

Covid-19 vaccines

Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination

https://pubmed.ncbi.nlm.nih.gov/39424883/

No link between type I interferon autoantibody positivity and adverse reactions to COVID-19 vaccines

https://pubmed.ncbi.nlm.nih.gov/38388530/

Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination
https://pubmed.ncbi.nlm.nih.gov/40341528/

Atypical femur fractures

Gene-based association analysis of a large patient cohort provides insights into genetics of atypical femur fractures

https://pubmed.ncbi.nlm.nih.gov/39126371/

A Genome-Wide Association Study of Bisphosphonate-Associated Atypical Femoral Fracture

https://pubmed.ncbi.nlm.nih.gov/31006051/

Central nervous system toxicity

Whole genome case-control study of central nervous system toxicity due to antimicrobial drugs

https://pubmed.ncbi.nlm.nih.gov/38422004/

Narcolepsy

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

https://pubmed.ncbi.nlm.nih.gov/37188663/

Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival

https://pubmed.ncbi.nlm.nih.gov/30711515/

Liver toxicity

Genome-wide association study of liver enzyme elevation in an extended cohort of rheumatoid arthritis patients starting low-dose methotrexate

https://pubmed.ncbi.nlm.nih.gov/36070248/

Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patients starting methotrexate

https://pubmed.ncbi.nlm.nih.gov/34521259/

MTHFR,TYMS and SLCO1B1 polymorphisms and adverse liver effects of methotrexate in rheumatoid arthritis

https://pubmed.ncbi.nlm.nih.gov/32024416/

A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury

https://pubmed.ncbi.nlm.nih.gov/30664875/

Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles

https://pubmed.ncbi.nlm.nih.gov/30661239/

Clinical factors predicting drug-induced liver injury due to flucloxacillin

https://pubmed.ncbi.nlm.nih.gov/30538582/

Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis

https://pubmed.ncbi.nlm.nih.gov/30013178/

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

https://pubmed.ncbi.nlm.nih.gov/28043905/

Shared Genetic Risk Factors Across Carbamazepine‐Induced Hypersensitivity Reactions

https://pubmed.ncbi.nlm.nih.gov/31066027/

Angiodema

Molecular Genetic Screening in Patients With ACE Inhibitor/Angiotensin Receptor Blocker-Induced Angioedema to Explore the Role of Hereditary Angioedema Genes

https://pubmed.ncbi.nlm.nih.gov/35923707/

Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker-Induced Angioedema

https://pubmed.ncbi.nlm.nih.gov/32496628/

Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment

https://pubmed.ncbi.nlm.nih.gov/32080354/

Comparison of Clinical Factors Between Patients With Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema and Cough

https://pubmed.ncbi.nlm.nih.gov/27889699/

Cough

Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population

https://pubmed.ncbi.nlm.nih.gov/28084903/

Comparison of Clinical Factors Between Patients With Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema and Cough

https://pubmed.ncbi.nlm.nih.gov/27889699/

Agranulocytosis

Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations

https://pubmed.ncbi.nlm.nih.gov/33138277/

High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis

https://pubmed.ncbi.nlm.nih.gov/32973882/

Sulfasalazine-Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus

https://pubmed.ncbi.nlm.nih.gov/28762467/

Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population

https://pubmed.ncbi.nlm.nih.gov/27157822/

Myopathy

Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

https://pubmed.ncbi.nlm.nih.gov/31242253/

Fusidic Acid: A Neglected Risk Factor for Statin-Associated Myopathy

https://pubmed.ncbi.nlm.nih.gov/30618488/

A common missense variant of LILRB5 is associated with statin intolerance and myalgia

https://pubmed.ncbi.nlm.nih.gov/29020356/

Serious cutaneous adverse reactions

Shared Genetic Risk Factors Across Carbamazepine‐Induced Hypersensitivity Reactions

https://pubmed.ncbi.nlm.nih.gov/31066027/

Osteonecrosis

Time to onset of bisphosphonate-related osteonecrosis of the jaws: a multicentre retrospective cohort study

https://pubmed.ncbi.nlm.nih.gov/28039941/

Pancreatitis

HLA variants associated with azathioprine-induced pancreatitis in patients with Crohn's disease

https://pubmed.ncbi.nlm.nih.gov/35120281/