Current status

As of June 1, 2017, the below number of cases have been recruited in Swedegene. DNA and clinical data collection for these cases are completed.


ADR type Number of cases
Angioedema (mainly related to ACE-inhibitors/ARBs) 479
Cough related to ACE-inhibitors 151
Osteonecrosis and atypical fractures due to bisphosphonates 107
Phototoxic reactions (mainly due to topical NSAIDs) 48
Drug hypersensitivity, mainly antibiotics and NSAIDs 313
Metabolic reactions from neuroleptics and antidepressants (mainly weight gain) 46
Hyponatremia/SIADH due to antidepressants and antiepileptics 36
CNS toxicity and neuropsychiatric reactions from antiviral therapy and antibiotics 80
Stevens-Johnson syndrome/Toxic epidermal necrolysis 58
Tendon-rupture from flouroquinolones 24
Liver toxicity 270
Rhabdomyolysis related to statins/fibrates 48
Torsade de Pointes/QT-prolongation 17
Agranulocytosis and neutropenia from non-chemotherapeutic agents 172
Thrombocytopenia 51
Narcolepsy associated with Pandemrix 64
Pancreatitis 79
Ototoxicity and vestibular toxicity 6
Alopecia 26
Bleedings from new oral anticoagulants (NOACs) 52
Other blood cell dyscrasia 15
Renal toxicity 50
Other 342
Total number of cases 2529

ACE = angiotensin converting enzyme; ARB = angiotensin II type 1 receptor blocker; NSAID = non-steroidal anti-inflammatory drug.

Note that the number of cases for a particular ADR may be greater than the total number of cases as some individuals have experienced multiple ADRs concomitantly.